Csf2ra
WebApr 13, 2024 · 构建重组asfv- cd2v缺失毒株可下调jak2-stat3信号通路,诱导细胞凋亡。酵母双杂交系统筛选发现病毒蛋白cd2v与宿主蛋白csf2ra互作(图c),csf2ra是存在于髓系细胞中造血受体超家族成员,具有上调jak2和stat3蛋白表达水平的功能。 WebMar 9, 2024 · Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder caused by recessive mutations in GM-CSF receptor subunit α/β genes (CSF2RA/CSF2RB, respectively) characterized by impaired GM-CSF-dependent surfactant clearance by alveolar macrophages (AMs) resulting in alveolar surfactant accumulation and …
Csf2ra
Did you know?
WebJun 24, 2024 · In this larger cohort, we tested the cis-and trans effect of the four variants associated with reduced GMSI level, on gene expression of RCL1, GM-CSF signaling genes (CSF2RA, CSF2RB, JAK2 STAT5A ... WebCSF2RA. colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages.
WebJan 5, 2024 · Orthologous to human CSF2RA (colony stimulating factor 2 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2024] Other designations. granulocyte-macrophage colony-stimulating factor receptor subunit alpha, GM-CSF-R-alpha, GM-CSFRalpha, GMCSFR-alpha, GMR-alpha, colony stimulating factor 2 receptor … WebThe colony stimulating factor 2 receptor alpha (Csf2ra) gene encodes GM-CSF receptor a (CD116) in mice. Defective GM-CSF receptor signaling results in abnormal development and functionality of
WebSep 20, 2024 · SDS–PAGE and western blotting. Results Csf2ra KO mice acquire protection from RT-induced mortality and morbidity. To investigate the role of Csf2ra on the survival time of mice after RT challenge, Csf2ra KO (n = 10) and WT (n = 10) mice were challenged with 2 × LD 50 of RT by aerosolized intratracheal inoculation. We recorded … WebAug 18, 2009 · Using an expression cloning strategy, Gearing et al. (1989) isolated a cDNA encoding CSF2RA, which they called GMCSFR, from a human placenta cDNA library. …
WebCSF2RA, “Colony stimulating factor 2 receptor alpha subunit (CD116)”, is a re-ceptor for GM-CSF (granulocyte-macrophage colony-stimulating factor), and plays a vital role for proliferation, differentiation and functional activation of hematopoietic cells such as macrophages and leukocytes . The absence of [1]
WebNov 26, 2014 · Juvenile pulmonary alveolar proteinosis (PAP) due to CSF2RA mutations is a rare disorder with only a few cases described worldwide. We identified nine children … bistro philippin tagesessenWebJun 1, 2024 · To address the role of GM-CSF receptor signaling in the pathogenesis of chronic airway inflammation in vivo, we used Csf2ra −/− mice, which were transplanted … bistro pfiff altbachWebLow affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of … bistro philly cheeseWebDescription: Homo sapiens colony stimulating factor 2 receptor subunit alpha (CSF2RA), transcript variant 7, mRNA. (from RefSeq NM_001161529) RefSeq Summary (NM_001161529): The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the … bistro petit brooklynWebThe protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a c ytokine which controls the production, differentiation, and … dart trackingWebMar 29, 2024 · CSF2RA colony stimulating factor 2 receptor subunit alpha Gene ID: 1438, updated on 29-Mar-2024 Gene type: protein coding Also known as: GMR; CD116; … bistro persian restaurants in great neckWebAntibodies that detect CSF2RA (CD116) can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry … bistro patio table with umbrella